Twenty two years after a tragic accident leaves one sorority sister dead, Michelle, a surviving sister, is now the dean of the university. As her own daughter reaches college age, mysterious events begin to occur and old secrets emerge that could not only damage Michelle's reputation, but could also put her daughter in serious danger.

After catching her long-term boyfriend cheating, Jenna turns toward elements she doesn't fully understand to get revenge. Said vengeance comes in the form of a succubus named Lillith, who embarks on a bloodthirsty, sex-fueled rampage.