A Group of college students head to Mexico for some cheap plastic surgery. There they meet Dr. Pavor, a creepy surgeon who is actually a vampire, harvesting victims for his blood cartel. Aided by his blood thirsty nurses he systematically carries out his evil plan. When a detective looking for his missing daughter arrives - all hell breaks loose in a bloody combustible conclusion.

Os gritos das crianças ecoam durante toda a noite como uma lembrança violenta de um demônio do passado. La Llorona, uma força paranormal voltou e procura o sangue dos inocentes, provando que a lenda é real.