Reeling from the grief of a failed adoption, the Barnett family gets a second chance when they get a call about a little girl named Natalia.

After firing some of Grey Sloan's best, Catherine continues to interfere with Meredith and Amelia's research; accidents at a climate change protest bring unique cases to the hospital; Bailey encounters a blast from the past.

Um agente do FBI decide colocar o vigarista Frank Abagnale Jr. atrás das grades. Contudo, além de escapar constantemente, Frank se diverte com a perseguição.