For Cheo Martínez, embittering the lives of others has become a daily practice, since he seems to enjoy the role of undesirable. His neighbors, tired of the difficult coexistence, decide to use a desperate strategy: hire a woman who makes him fall in love and convinces him to leave the building. But they don't hire just anyone. Carolina Rico, a bold and beautiful prostitute, accepts the job to escape from an evil mobster. However, the neighbors' plan falls apart because Cheo and Carolina fall in love.

Anos após o conquistador espanhol Pedro de Heredia trair o povo dela e partir seu coração, a índia Catalina reaparece na vida dele em busca de vingança.