Inspired by Sir Arthur Conan Doyle's classic literary characters, the series follows Dr. Wato-san Tachibana and Sara Shelly "Sherlock" Futaba, an eccentric police consultant who uses deduction to solve strange cases in modern-day Japan.

Two historical incidents that deepened the friendship between Japan and Turkey are connected: The sinking of the Turkish frigate Ertugrul off the Japanese coast in 1890 and the evacuation of Japanese nationals from Iran in 1985.

O maléfico Makoto Shishio tenta derrubar o governo Meji. Kenshin Himura não tem outra escolha a não ser sacar a espada mais uma vez (apesar de ter prometido não